FZD8

GENE INFORMATION

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Gene name

FZD8

Synonyms

Description

frizzled family receptor 8 (HGNC Symbol)

Entrez gene summary

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

p11.21

Chromosome location (bp)

35927177 - 35930362

Ensembl

ENSG00000177283 (version 73.37)

Entrez gene

8325

UniProt

Q9H461 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H461

Antibodypedia

FZD8 antibodies
 

PROTEIN VIEW

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FZD8-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FZD8-001 ENSP00000363826
ENST00000374694
Q9H461
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Show » Show » 694 73.3 Yes 7