CD163

GENE INFORMATION

? »

Gene name

CD163 (HGNC Symbol)

Synonyms

M130, MM130

Description

CD163 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Chromosome

12 (Chromosome progress)

Cytoband

p13.31

Chromosome location (bp)

7623409 - 7656489

Ensembl

ENSG00000177575 (version 73.37)

Entrez gene

9332

UniProt

Q86VB7 (UniProt - Evidence at protein level)

neXtProt

NX_Q86VB7

Antibodypedia

CD163 antibodies
 

PROTEIN VIEW

? »
 
 
 
CD163-001
 
CD163-002
 
CD163-003
 
CD163-005
 
CD163-007
 
CD163-009
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD163-001 ENSP00000352071
ENST00000359156
Q86VB7
Show all »
Show » Show » 1156 125.5 No 1
CD163-002 ENSP00000403885
ENST00000432237
Q86VB7
Show all »
Show » Show » 1121 121.6 No 1
CD163-003 ENSP00000379863
ENST00000396620
C9JHR8
Show all »
Show » Show » 1154 124.9 No 1
CD163-005 ENSP00000444071
ENST00000541972
F5GZZ9
Show all »
Show » Show » 1109 120.3 Yes 1
CD163-007 ENSP00000439226
ENST00000537626
Show » Show » 137 15 No 1
CD163-009 ENSP00000445438
ENST00000542280
H0YGZ7
Show all »
Show » 124 13.4 No 0