CD163L1

GENERAL INFORMATION

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Gene name

CD163L1

Gene description

CD163 molecule-like 1

Protein class

CD markers
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (spleen)
GTEx:Tissue enhanced (spleen)

Protein evidence

Evidence at protein level

Protein localization

High cytoplasmic expression in a subset of lymphoid cells.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Supportive based on 1 antibody.
HPA015663
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Spleen

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression



GENE INFORMATION

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Gene name

CD163L1 (HGNC Symbol)

Synonyms

CD163B, M160

Description

CD163 molecule-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

7346685 - 7479897

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177675 (version 78.38)

Entrez gene

283316

UniProt

Q9NR16 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NR16

Antibodypedia

CD163L1 antibodies


PROTEIN BROWSER

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ENST00000313599
 
ENST00000416109
 
ENST00000539726
 
ENST00000543276
 
ENST00000545926
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD163L1-001 ENSP00000315945
ENST00000313599
Q9NR16
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Show » Show » 1453 159.2 No 1
CD163L1-002 ENSP00000393474
ENST00000416109
Q9NR16
Show all »
Show » Show » 1463 160.3 No 1
CD163L1-003 ENSP00000439921
ENST00000545926
H0YFR4
Show all »
Show » Show » 189 20.8 No 0
CD163L1-006 ENSP00000438217
ENST00000539726
Show » 109 11.9 No 1
CD163L1-010 ENSP00000442328
ENST00000543276
F5H7R7
Show all »
Show » Show » 62 7.1 No 0