NDUFV2

GENERAL INFORMATION

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Gene name

NDUFV2

Gene description

NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa

Protein class

Enzymes
Mitochondrial proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA003404
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

NDUFV2 (HGNC Symbol)

Synonyms

CI-24k

Description

NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (HGNC Symbol)

Entrez gene summary

The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]

Chromosome

18

Cytoband

p11.22

Chromosome location (bp)

9102630 - 9134345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178127 (version 78.38)

Entrez gene

4729

UniProt

P19404 (UniProt - Evidence at protein level)

neXtProt

NX_P19404

Antibodypedia

NDUFV2 antibodies


PROTEIN BROWSER

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ENST00000318388
 
ENST00000400033
 
ENST00000497577
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NDUFV2-001 ENSP00000327268
ENST00000318388
P19404
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Show » Show » 249 27.4 No 0
NDUFV2-002 ENSP00000382908
ENST00000400033
E7EPT4
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Show » Show » 252 27.9 No 0
NDUFV2-003 ENSP00000464504
ENST00000497577
J3QS34
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Show » 21 2.4 No 0