ERN1

GENE INFORMATION

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Gene name

ERN1 (HGNC Symbol)

Synonyms

IRE1, IRE1P

Description

endoplasmic reticulum to nucleus signaling 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

62120353 - 62208179

Ensembl

ENSG00000178607 (version 73.37)

Entrez gene

2081

UniProt

O75460 (UniProt - Evidence at protein level)

neXtProt

NX_O75460

Antibodypedia

ERN1 antibodies
 

PROTEIN VIEW

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ERN1-001
 
ERN1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ERN1-001 ENSP00000401445
ENST00000433197
O75460
Show all »
Show » Show » 977 109.7 Yes 2
ERN1-008 ENSP00000475519
ENST00000606895
70 6.6 Yes 0