PFAS

GENE INFORMATION

? »

Gene name

PFAS (HGNC Symbol)

Synonyms

FGARAT, KIAA0361, PURL

Description

phosphoribosylformylglycinamidine synthase (HGNC Symbol)

Entrez gene summary

Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

8150936 - 8173809

Ensembl

ENSG00000178921 (version 73.37)

Entrez gene

5198

UniProt

O15067 (UniProt - Evidence at protein level)

neXtProt

NX_O15067

Antibodypedia

PFAS antibodies
 

PROTEIN VIEW

? »
 
 
 
PFAS-001
 
PFAS-002
 
PFAS-003
 
PFAS-004
 
PFAS-005
 
PFAS-007
 
PFAS-008
 
PFAS-011
 
PFAS-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PFAS-001 ENSP00000313490
ENST00000314666
O15067
Show all »
Show » Show » 1338 144.7 No 0
PFAS-002 ENSP00000464671
ENST00000580356
J3QSG0
Show all »
Show » 131 14.6 No 0
PFAS-003 ENSP00000462874
ENST00000583059
117 12.2 No 0
PFAS-004 ENSP00000443244
ENST00000546020
385 41.2 No 0
PFAS-005 ENSP00000463362
ENST00000585183
J3QL39
Show all »
Show » 88 9.8 No 0
PFAS-007 ENSP00000464689
ENST00000584044
J3QSH6
Show all »
Show » 135 14.9 No 0
PFAS-008 ENSP00000463045
ENST00000581242
J3KTL4
Show all »
Show » 103 11.4 No 0
PFAS-011 ENSP00000463103
ENST00000578979
62 6.4 No 0
PFAS-201 ENSP00000441706
ENST00000545834
F5GWT9
Show all »
Show » Show » 914 97.7 No 0