GAK

GENE INFORMATION

? »

Gene name

GAK (HGNC Symbol)

Synonyms

DNAJC26

Description

cyclin G associated kinase (HGNC Symbol)

Entrez gene summary

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p16.3

Chromosome location (bp)

843064 - 926161

Ensembl

ENSG00000178950 (version 73.37)

Entrez gene

2580

UniProt

O14976 (UniProt - Evidence at protein level)

neXtProt

NX_O14976

Antibodypedia

GAK antibodies
 

PROTEIN VIEW

? »
 
 
 
GAK-001
 
GAK-002
 
GAK-003
 
GAK-010
 
GAK-011
 
GAK-015
 
GAK-019
 
GAK-020
 
GAK-022
 
GAK-024
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GAK-001 ENSP00000314499
ENST00000314167
O14976
Show all »
Show » Show » 1311 143.2 No 0
GAK-002 ENSP00000421361
ENST00000511163
E9PGR2
Show all »
Show » Show » 1232 134.5 No 0
GAK-003 ENSP00000426908
ENST00000505819
D6RE78
Show all »
Show » 118 12.4 No 0
GAK-010 ENSP00000426062
ENST00000510799
255 25.4 No 0
GAK-011 ENSP00000421049
ENST00000511980
Show » 467 49 No 0
GAK-015 ENSP00000422391
ENST00000511229
D6RC24
Show all »
Show » 70 7.8 No 0
GAK-019 ENSP00000421814
ENST00000512325
D6RAQ7
Show all »
Show » 75 8.1 No 0
GAK-020 ENSP00000424701
ENST00000502656
D6RAW3
Show all »
Show » 138 15.2 No 0
GAK-022 ENSP00000426728
ENST00000507580
D6RF16
Show all »
49 5.1 No 0
GAK-024 ENSP00000424553
ENST00000504668
H0Y9M4
Show all »
69 7.5 No 0