ALOX15B

GENE INFORMATION

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Gene name

ALOX15B (HGNC Symbol)

Synonyms

15-LOX-2

Description

arachidonate 15-lipoxygenase, type B (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

7942335 - 7952452

Ensembl

ENSG00000179593 (version 73.37)

Entrez gene

247

UniProt

O15296 (UniProt - Evidence at transcript level)

neXtProt

NX_O15296

Antibodypedia

ALOX15B antibodies
 

PROTEIN VIEW

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ALOX15B-001
 
ALOX15B-002
 
ALOX15B-005
 
ALOX15B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALOX15B-001 ENSP00000369530
ENST00000380183
O15296
Show all »
Show » Show » 676 75.9 No 0
ALOX15B-002 ENSP00000458749
ENST00000572022
I3L1D5
Show all »
Show » Show » 664 74.5 No 0
ALOX15B-005 ENSP00000460332
ENST00000573359
O15296
Show all »
Show » Show » 602 67.3 No 0
ALOX15B-201 ENSP00000369520
ENST00000380173
O15296
Show all »
Show » Show » 647 72.5 No 0