PUF60

GENE INFORMATION

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Gene name

PUF60 (HGNC Symbol)

Synonyms

FIR, RoBPI, SIAHBP1

Description

poly-U binding splicing factor 60KDa (HGNC Symbol)

Entrez gene summary

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Chromosome

8 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

144898514 - 144912029

Ensembl

ENSG00000179950 (version 73.37)

Entrez gene

22827

UniProt

Q9UHX1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHX1

Antibodypedia

PUF60 antibodies
 

PROTEIN VIEW

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 « 
 
PUF60-001
 
PUF60-002
 
PUF60-003
 
PUF60-004
 
PUF60-005
 
PUF60-006
 
PUF60-011
 
PUF60-012
 
PUF60-013
 
PUF60-023
 
PUF60-024
 
PUF60-025
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PUF60-001 ENSP00000434359
ENST00000526683
Q9UHX1
Show all »
Show » 559 59.9 No 0
PUF60-002 ENSP00000322036
ENST00000349157
Q9UHX1
Show all »
Show » 542 58.2 No 0
PUF60-003 ENSP00000402953
ENST00000453551
Q9UHX1
Show all »
Show » 516 55.7 No 0
PUF60-004 ENSP00000322016
ENST00000313352
Q9UHX1
Show all »
Show » 499 54 No 0
PUF60-005 ENSP00000395417
ENST00000456095
Q9UHX1
Show all »
Show » 530 57.1 No 0
PUF60-006 ENSP00000431960
ENST00000527197
Q9UHX1
Show all »
Show » 513 55.4 No 0
PUF60-011 ENSP00000433403
ENST00000533162
E9PL19
Show all »
Show » 228 24.8 No 0
PUF60-012 ENSP00000434863
ENST00000529999
E9PN18
Show all »
Show » 263 28.7 No 0
PUF60-013 ENSP00000437309
ENST00000531897
E9PMU7
Show all »
Show » 247 26.9 No 0
PUF60-023 ENSP00000432091
ENST00000532884
Show » 273 28.1 No 0
PUF60-024 ENSP00000432610
ENST00000526459
E9PQ56
Show all »
Show » 323 34.5 No 0
PUF60-025 ENSP00000436131
ENST00000527744
Show » 336 35.7 No 0