The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Most of the normal tissues displayed moderate cytoplasmic positivity. Subset of cells in intestinal tract, renal tubules, lung macrophages, myoepithelial cells, plasma and fraction of cells in seminiferous ducts showed strong staining. Decidual cells, prostate, spleen and tonsil were negative.
Gastrointestinal tract, bronchus, hepatocytes, kidney, exocrine pancreas, adrenal gland, squamous epithelia, postmenopausal uterine glands, cervix, heart muscle and seminal vesicle showed moderate to strong cytoplasmic positivity in fraction of cells. Remaining normal tissues were weakly stained or negative.
Weak to moderate cytoplasmic positivity was seen in most normal tissues. Distinct extracellular staining was observed in most tissues. Glandular cells of salivary gland and Purkinje cells displayed strong positivity.
Most normal tissues displayed weak cytoplasmic staining or were negative. Strong staining was observed in breast glands and Leydig cells in testis while moderate cytoplasmic immunoreactivity was observed in renal tubules and Purkinje cells. Plasma was distinctly stained.