PAK2

GENE INFORMATION

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Gene name

PAK2 (HGNC Symbol)

Synonyms

PAK65, PAKgamma

Description

p21 protein (Cdc42/Rac)-activated kinase 2 (HGNC Symbol)

Entrez gene summary

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q29

Chromosome location (bp)

196466728 - 196559518

Ensembl

ENSG00000180370 (version 73.37)

Entrez gene

5062

UniProt

Q13177 (UniProt - Evidence at protein level)

neXtProt

NX_Q13177

Antibodypedia

PAK2 antibodies
 

PROTEIN VIEW

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PAK2-001
 
PAK2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAK2-001 ENSP00000314067
ENST00000327134
Q13177
Show all »
Show » Show » 524 58 No 0
PAK2-004 ENSP00000402927
ENST00000426668
Show » Show » 221 24.4 No 0