S1PR5

GENE INFORMATION

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Gene name

S1PR5 (HGNC Symbol)

Synonyms

Edg-8, EDG8

Description

sphingosine-1-phosphate receptor 5 (HGNC Symbol)

Entrez gene summary

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

10623623 - 10628607

Ensembl

ENSG00000180739 (version 73.37)

Entrez gene

53637

UniProt

Q9H228 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H228

Antibodypedia

S1PR5 antibodies
 

PROTEIN VIEW

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S1PR5-001
 
S1PR5-004
 
S1PR5-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

S1PR5-001 ENSP00000328472
ENST00000333430
Q9H228
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Show » Show » 398 41.8 No 7
S1PR5-004 ENSP00000416915
ENST00000439028
Q9H228
Show all »
Show » Show » 398 41.8 No 7
S1PR5-007 ENSP00000464884
ENST00000590601
K7EIT5
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Show » Show » 75 8.1 No 0