MAP3K15

GENE INFORMATION

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Gene name

MAP3K15 (HGNC Symbol)

Synonyms

bA723P2.3, FLJ16518

Description

mitogen-activated protein kinase kinase kinase 15 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses. [provided by RefSeq, Jul 2010]

Chromosome

X (Chromosome progress)

Cytoband

p22.12

Chromosome location (bp)

19378174 - 19533379

Ensembl

ENSG00000180815 (version 73.37)

Entrez gene

389840

UniProt

Q6ZN16 (UniProt - Evidence at protein level)

neXtProt

NX_Q6ZN16

Antibodypedia

MAP3K15 antibodies
 

PROTEIN VIEW

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MAP3K15-001
 
MAP3K15-004
 
MAP3K15-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP3K15-001 ENSP00000428356
ENST00000469203
E7EWI5
Show all »
Show » Show » 1145 130.7 No 0
MAP3K15-004 ENSP00000352093
ENST00000359173
Q6ZN16
Show all »
Show » Show » 748 84.7 No 0
MAP3K15-201 ENSP00000345629
ENST00000338883
Q6ZN16
Show all »
Show » Show » 1313 147.4 No 0