SCRIB

GENE INFORMATION

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Gene name

SCRIB (HGNC Symbol)

Synonyms

KIAA0147, SCRB1, Vartul

Description

scribbled planar cell polarity protein (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Chromosome

8 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

144873090 - 144897549

Ensembl

ENSG00000180900 (version 73.37)

Entrez gene

23513

UniProt

Q14160 (UniProt - Evidence at protein level)

neXtProt

NX_Q14160

Antibodypedia

SCRIB antibodies
 

PROTEIN VIEW

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SCRIB-001
 
SCRIB-002
 
SCRIB-003
 
SCRIB-004
 
SCRIB-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SCRIB-001 ENSP00000322938
ENST00000320476
Q14160
Show all »
Show » 1630 174.9 No 0
SCRIB-002 ENSP00000349486
ENST00000356994
Q14160
Show all »
Show » 1655 177.7 No 0
SCRIB-003 ENSP00000366756
ENST00000377533
Q14160
Show all »
Show » 1549 165.2 No 0
SCRIB-004 ENSP00000431519
ENST00000526832
Show » 650 68.3 No 0
SCRIB-007 ENSP00000433546
ENST00000531942
H0YDF9
Show all »
Show » 140 14.9 No 0