MRPL14

GENE INFORMATION

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Gene name

MRPL14 (HGNC Symbol)

Synonyms

MRP-L32, RPML32

Description

mitochondrial ribosomal protein L14 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p21.1

Chromosome location (bp)

44081194 - 44095194

Ensembl

ENSG00000180992 (version 73.37)

Entrez gene

64928

UniProt

Q6P1L8 (UniProt - Evidence at protein level)

neXtProt

NX_Q6P1L8

Antibodypedia

MRPL14 antibodies
 

PROTEIN VIEW

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MRPL14-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL14-001 ENSP00000361084
ENST00000372014
Q6P1L8
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