AATK

GENE INFORMATION

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Gene name

AATK (HGNC Symbol)

Synonyms

AATYK, AATYK1, KIAA0641, LMR1, LMTK1

Description

apoptosis-associated tyrosine kinase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Chromosome

17 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

79091095 - 79139877

Ensembl

ENSG00000181409 (version 73.37)

Entrez gene

9625

UniProt

Q6ZMQ8 (UniProt - Evidence at protein level)

neXtProt

NX_Q6ZMQ8

Antibodypedia

AATK antibodies
 

PROTEIN VIEW

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AATK-001
 
AATK-002
 
AATK-003
 
AATK-004
 
AATK-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AATK-001 ENSP00000324196
ENST00000326724
Q6ZMQ8
Show all »
Show » Show » 1374 144.6 No 1
AATK-002 ENSP00000398796
ENST00000417379
H7C175
Show all »
Show » Show » 1271 133.8 No 0
AATK-003 ENSP00000460986
ENST00000570932
I3L461
Show all »
105 11 No 0
AATK-004 ENSP00000363924
ENST00000374792
Q6ZMQ8
Show all »
Show » Show » 879 93.2 No 1
AATK-006 ENSP00000460202
ENST00000575363
I3L360
Show all »
Show » 116 12.5 No 0