SLC2A4

GENE INFORMATION

? »

Gene name

SLC2A4 (HGNC Symbol)

Synonyms

GLUT4

Description

solute carrier family 2 (facilitated glucose transporter), member 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

7184986 - 7191576

Ensembl

ENSG00000181856 (version 73.37)

Entrez gene

6517

UniProt

P14672 (UniProt - Evidence at protein level)

neXtProt

NX_P14672

Antibodypedia

SLC2A4 antibodies
 

PROTEIN VIEW

? »
 
 
 
SLC2A4-001
 
SLC2A4-002
 
SLC2A4-003
 
SLC2A4-004
 
SLC2A4-005
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC2A4-001 ENSP00000320935
ENST00000317370
P14672
Show all »
Show » Show » 509 54.8 No >9
SLC2A4-002 ENSP00000461086
ENST00000572485
Q05BQ3
Show all »
Show » Show » 415 43.8 No 8
SLC2A4-003 ENSP00000459864
ENST00000571308
I3L2R4
Show all »
Show » Show » 461 49 No >9
SLC2A4-004 ENSP00000396887
ENST00000424875
F5H081
Show all »
Show » Show » 451 48 No >9
SLC2A4-005 ENSP00000459056
ENST00000570783
I3L1S2
Show all »
Show » Show » 219 22.7 No 5