MRPS11

GENE INFORMATION

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Gene name

MRPS11 (HGNC Symbol)

Synonyms

FLJ22512, FLJ23406, HCC-2

Description

mitochondrial ribosomal protein S11 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

89010684 - 89022222

Ensembl

ENSG00000181991 (version 73.37)

Entrez gene

64963

UniProt

P82912 (UniProt - Evidence at protein level)

neXtProt

NX_P82912

Antibodypedia

MRPS11 antibodies
 

PROTEIN VIEW

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MRPS11-001
 
MRPS11-002
 
MRPS11-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS11-001 ENSP00000317376
ENST00000325844
P82912
Show all »
Show » Show » 194 20.6 No 0
MRPS11-002 ENSP00000318054
ENST00000353598
P82912
Show all »
Show » Show » 161 16.9 No 0
MRPS11-004 ENSP00000453116
ENST00000560708
H0YL99
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Show » 118 13 No 0