NOP10

GENE INFORMATION

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Gene name

NOP10 (HGNC Symbol)

Synonyms

MGC70651, NOLA3, NOP10P

Description

NOP10 ribonucleoprotein (HGNC Symbol)

Entrez gene summary

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q14

Chromosome location (bp)

34633917 - 34635378

Ensembl

ENSG00000182117 (version 73.37)

Entrez gene

55505

UniProt

Q9NPE3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPE3

Antibodypedia

NOP10 antibodies
 

PROTEIN VIEW

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NOP10-001
 
NOP10-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NOP10-001 ENSP00000332198
ENST00000328848
Q9NPE3
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Show » 64 7.7 No 0
NOP10-002 ENSP00000453475
ENST00000557912
H0YM60
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36 4.2 No 0