MRPS16

GENE INFORMATION

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Gene name

MRPS16 (HGNC Symbol)

Synonyms

CGI-132

Description

mitochondrial ribosomal protein S16 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

75006510 - 75012451

Ensembl

ENSG00000182180 (version 73.37)

Entrez gene

51021

UniProt

Q9Y3D3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y3D3

Antibodypedia

MRPS16 antibodies
 

PROTEIN VIEW

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MRPS16-001
 
MRPS16-005
 
MRPS16-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS16-001 ENSP00000362036
ENST00000372945
Q9Y3D3
Show all »
Show » Show » 137 15.3 No 0
MRPS16-005 ENSP00000362031
ENST00000372940
A6ND22
Show all »
Show » 99 11.2 No 0
MRPS16-201 ENSP00000408812
ENST00000416782
B4E032
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Show » 123 13.8 No 0