SYNM

GENE INFORMATION

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Gene name

SYNM (HGNC Symbol)

Synonyms

DMN, KIAA0353, SYN

Description

synemin, intermediate filament protein (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

99638420 - 99675798

Ensembl

ENSG00000182253 (version 73.37)

Entrez gene

23336

UniProt

O15061 (UniProt - Evidence at protein level)

neXtProt

NX_O15061

Antibodypedia

SYNM antibodies
 

PROTEIN VIEW

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SYNM-003
 
SYNM-201
 
SYNM-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYNM-003 ENSP00000453040
ENST00000560674
H0YL34
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Show » 967 107.1 No 0
SYNM-201 ENSP00000330469
ENST00000328642
C9JIE4
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Show » 1252 140 No 0
SYNM-202 ENSP00000336775
ENST00000336292
O15061
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Show » 1564 172.7 No 0