KCNA4

GENE INFORMATION

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Gene name

KCNA4 (HGNC Symbol)

Synonyms

HK1, HPCN2, KCNA4L, Kv1.4

Description

potassium voltage-gated channel, shaker-related subfamily, member 4 (HGNC Symbol)

Entrez gene summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011]

Chromosome

11 (Chromosome progress)

Cytoband

p14.1

Chromosome location (bp)

30031288 - 30038570

Ensembl

ENSG00000182255 (version 73.37)

Entrez gene

3739

UniProt

P22459 (UniProt - Evidence at protein level)

neXtProt

NX_P22459

Antibodypedia

KCNA4 antibodies
 

PROTEIN VIEW

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KCNA4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNA4-001 ENSP00000328511
ENST00000328224
P22459
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