GABRG3

GENE INFORMATION

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Gene name

GABRG3

Synonyms

Description

gamma-aminobutyric acid (GABA) A receptor, gamma 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]

Chromosome

15 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

27216429 - 27778373

Ensembl

ENSG00000182256 (version 73.37)

Entrez gene

2567

UniProt

Q99928 (UniProt - Evidence at transcript level)

neXtProt

NX_Q99928

Antibodypedia

GABRG3 antibodies
 

PROTEIN VIEW

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GABRG3-001
 
GABRG3-002
 
GABRG3-004
 
GABRG3-005
 
GABRG3-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GABRG3-001 ENSP00000331912
ENST00000333743
Q99928
Show all »
Show » Show » 467 54.3 Yes 4
GABRG3-002 ENSP00000452244
ENST00000555083
G3V594
Show all »
Show » 253 29.4 Yes 0
GABRG3-004 ENSP00000390708
ENST00000451330
Show » Show » 169 19 No 3
GABRG3-005 ENSP00000451862
ENST00000554696
H0YJP1
Show all »
Show » Show » 258 30 No 2
GABRG3-007 ENSP00000450976
ENST00000557596
Show » Show » 38 4.3 No 0