AP1S2

GENE INFORMATION

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Gene name

AP1S2 (HGNC Symbol)

Synonyms

MRX59, SIGMA1B

Description

adaptor-related protein complex 1, sigma 2 subunit (HGNC Symbol)

Entrez gene summary

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

Chromosome

X (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

15843929 - 15873054

Ensembl

ENSG00000182287 (version 73.37)

Entrez gene

8905

UniProt

P56377 (UniProt - Evidence at protein level)

neXtProt

NX_P56377

Antibodypedia

AP1S2 antibodies
 

PROTEIN VIEW

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AP1S2-001
 
AP1S2-002
 
AP1S2-003
 
AP1S2-004
 
AP1S2-201
 
AP1S2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AP1S2-001 ENSP00000328789
ENST00000329235
P56377
Show all »
Show » 157 18.6 No 0
AP1S2-002 ENSP00000403498
ENST00000452376
Show » 153 18 No 0
AP1S2-003 ENSP00000369645
ENST00000380291
A6NH01
Show all »
Show » 160 19.1 No 0
AP1S2-004 ENSP00000389474
ENST00000450644
Show » 146 17.4 No 0
AP1S2-201 ENSP00000414714
ENST00000421527
B4DSU4
Show all »
Show » 202 23.2 No 0
AP1S2-202 ENSP00000444957
ENST00000545766
B7Z3M9
Show all »
Show » 195 22.5 No 0