BGN

GENE INFORMATION

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Gene name

BGN (HGNC Symbol)

Synonyms

DSPG1, SLRR1A

Description

biglycan (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. [provided by RefSeq, Nov 2009]

Chromosome

X (Chromosome progress)

Cytoband

q28

Chromosome location (bp)

152760397 - 152775012

Ensembl

ENSG00000182492 (version 73.37)

Entrez gene

633

UniProt

P21810 (UniProt - Evidence at protein level)

neXtProt

NX_P21810

Antibodypedia

BGN antibodies
 

PROTEIN VIEW

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BGN-001
 
BGN-002
 
BGN-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BGN-001 ENSP00000327336
ENST00000331595
P21810
Show all »
Show » 368 41.7 Yes 0
BGN-002 ENSP00000402525
ENST00000431891
C9JKG1
Show all »
Show » 238 26.7 Yes 0
BGN-003 ENSP00000359223
ENST00000370204
A6NLG9
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Show » 307 34.9 No 0