FES

GENE INFORMATION

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Gene name

FES (HGNC Symbol)

Synonyms

FPS

Description

feline sarcoma oncogene (HGNC Symbol)

Entrez gene summary

This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]

Chromosome

15 (Chromosome progress)

Cytoband

q26.1

Chromosome location (bp)

91426925 - 91439006

Ensembl

ENSG00000182511 (version 73.37)

Entrez gene

2242

UniProt

P07332 (UniProt - Evidence at protein level)

neXtProt

NX_P07332

Antibodypedia

FES antibodies
 

PROTEIN VIEW

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 « 
 
FES-001
 
FES-003
 
FES-005
 
FES-006
 
FES-007
 
FES-010
 
FES-011
 
FES-017
 
FES-018
 
FES-019
 
FES-020
 
FES-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FES-001 ENSP00000331504
ENST00000328850
P07332
Show all »
Show » Show » 822 93.5 No 0
FES-003 ENSP00000435811
ENST00000464684
E9PIJ7
Show all »
Show » Show » 545 62.2 No 0
FES-005 ENSP00000377837
ENST00000394300
P07332
Show all »
Show » Show » 764 86.7 No 0
FES-006 ENSP00000377839
ENST00000394302
E7ENM8
Show all »
Show » 681 76.8 No 0
FES-007 ENSP00000410477
ENST00000416779
C9J3W6
Show all »
Show » 42 4.8 No 0
FES-010 ENSP00000392696
ENST00000452243
E7EMJ7
Show all »
Show » 147 16.9 No 0
FES-011 ENSP00000395425
ENST00000443697
E9PGC7
Show all »
Show » 115 13 No 0
FES-017 ENSP00000414629
ENST00000414248
P07332
Show all »
Show » Show » 694 78.6 No 0
FES-018 ENSP00000400868
ENST00000444422
P07332
Show all »
Show » Show » 752 85.5 No 0
FES-019 ENSP00000454146
ENST00000470152
H0YNT6
Show all »
Show » Show » 121 12.9 No 1
FES-020 ENSP00000454089
ENST00000559355
H0YNN8
Show all »
Show » 169 19.4 No 0
FES-201 ENSP00000409915
ENST00000450438
P07332
Show all »
Show » Show » 694 78.6 No 0