EPHB3

GENE INFORMATION

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Gene name

EPHB3 (HGNC Symbol)

Synonyms

ETK2, Hek2, Tyro6

Description

EPH receptor B3 (HGNC Symbol)

Entrez gene summary

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010]

Chromosome

3 (Chromosome progress)

Cytoband

q27.1

Chromosome location (bp)

184279572 - 184300197

Ensembl

ENSG00000182580 (version 73.37)

Entrez gene

2049

UniProt

P54753 (UniProt - Evidence at protein level)

neXtProt

NX_P54753

Antibodypedia

EPHB3 antibodies
 

PROTEIN VIEW

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EPHB3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHB3-001 ENSP00000332118
ENST00000330394
P54753
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