ASB7

GENERAL INFORMATION

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Gene name

ASB7

Gene description

Ankyrin repeat and SOCS box containing 7

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA003300
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Rectum

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ASB7

Synonyms

Description

Ankyrin repeat and SOCS box containing 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q26.3

Chromosome location (bp)

100602534 - 100651705

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183475 (version 78.38)

Entrez gene

140460

UniProt

Q9H672 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H672

Antibodypedia

ASB7 antibodies


PROTEIN BROWSER

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ENST00000332783
 
ENST00000343276
 
ENST00000558747
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ASB7-001 ENSP00000328327
ENST00000332783
Q9H672
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Show » Show » 318 36 No 0
ASB7-002 ENSP00000339819
ENST00000343276
Q9H672
Show all »
Show » Show » 274 30.7 No 0
ASB7-003 ENSP00000453626
ENST00000558747
H0YMJ1
Show all »
Show » Show » 116 13.4 No 0