ASB7

GENE INFORMATION

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Gene name

ASB7

Synonyms

Description

ankyrin repeat and SOCS box containing 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

101142739 - 101191910

Ensembl

ENSG00000183475 (version 73.37)

Entrez gene

140460

UniProt

Q9H672 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H672

Antibodypedia

ASB7 antibodies
 

PROTEIN VIEW

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ASB7-001
 
ASB7-002
 
ASB7-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ASB7-001 ENSP00000328327
ENST00000332783
Q9H672
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Show » 318 36 No 0
ASB7-002 ENSP00000339819
ENST00000343276
Q9H672
Show all »
Show » 274 30.7 No 0
ASB7-003 ENSP00000453626
ENST00000558747
H0YMJ1
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Show » 116 13.4 No 0