KCNH8

GENERAL INFORMATION

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Gene name

KCNH8

Gene description

Potassium voltage-gated channel, subfamily H (eag-related), member 8

Protein class

Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Tissue enhanced (cerebral cortex, hippocampus)

Protein evidence

Evidence at transcript level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

KCNH8 (HGNC Symbol)

Synonyms

elk3, Kv12.1

Description

Potassium voltage-gated channel, subfamily H (eag-related), member 8 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p24.3

Chromosome location (bp)

19148454 - 19535646

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000183960 (version 78.38)

Entrez gene

131096

UniProt

Q96L42 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96L42

Antibodypedia

KCNH8 antibodies


PROTEIN BROWSER

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ENST00000328405
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNH8-001 ENSP00000328813
ENST00000328405
Q96L42
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