ACTG1

GENE INFORMATION

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Gene name

ACTG1 (HGNC Symbol)

Synonyms

ACTG, DFNA20, DFNA26

Description

actin, gamma 1 (HGNC Symbol)

Entrez gene summary

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]

Chromosome

17 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

79476997 - 79490873

Ensembl

ENSG00000184009 (version 73.37)

Entrez gene

71

UniProt

P63261 (UniProt - Evidence at protein level)

neXtProt

NX_P63261

Antibodypedia

ACTG1 antibodies
 

PROTEIN VIEW

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 « 
 
ACTG1-001
 
ACTG1-002
 
ACTG1-003
 
ACTG1-006
 
ACTG1-010
 
ACTG1-011
 
ACTG1-012
 
ACTG1-013
 
ACTG1-014
 
ACTG1-015
 
ACTG1-017
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTG1-001 ENSP00000331514
ENST00000331925
P63261
Show all »
Show » 375 41.8 No 0
ACTG1-002 ENSP00000459124
ENST00000575087
P63261
Show all »
Show » 375 41.8 No 0
ACTG1-003 ENSP00000458435
ENST00000573283
P63261
Show all »
Show » 375 41.8 No 0
ACTG1-006 ENSP00000461672
ENST00000576544
P63261
Show all »
Show » 375 41.8 No 0
ACTG1-010 ENSP00000459119
ENST00000575659
I3L1U9
Show all »
Show » 214 23.8 No 0
ACTG1-011 ENSP00000460464
ENST00000575994
I3L1U9
Show all »
Show » 214 23.8 No 0
ACTG1-012 ENSP00000458162
ENST00000575842
P63261
Show all »
Show » 375 41.8 No 0
ACTG1-013 ENSP00000460660
ENST00000571721
I3L3R2
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Show » 164 18 No 0
ACTG1-014 ENSP00000466346
ENST00000570382
K7EM38
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Show » 133 14.5 No 0
ACTG1-015 ENSP00000462823
ENST00000572105
J3KT65
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Show » 198 21.8 No 0
ACTG1-017 ENSP00000461407
ENST00000571691
I3L4N8
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Show » 242 26.9 No 0