CSF1

GENE INFORMATION

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Gene name

CSF1 (HGNC Symbol)

Synonyms

M-CSF, MCSF, MGC31930

Description

colony stimulating factor 1 (macrophage) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Chromosome

1 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

110452864 - 110473614

Ensembl

ENSG00000184371 (version 73.37)

Entrez gene

1435

UniProt

P09603 (UniProt - Evidence at protein level)

neXtProt

NX_P09603

Antibodypedia

CSF1 antibodies
 

PROTEIN VIEW

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CSF1-001
 
CSF1-002
 
CSF1-003
 
CSF1-004
 
CSF1-005
 
CSF1-006
 
CSF1-007
 
CSF1-008
 
CSF1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CSF1-001 ENSP00000327513
ENST00000329608
P09603
Show all »
Show » Show » 554 60.2 Yes 1
CSF1-002 ENSP00000358817
ENST00000369802
P09603
Show all »
Show » Show » 554 60.2 Yes 1
CSF1-003 ENSP00000358816
ENST00000369801
P09603
Show all »
Show » Show » 438 47.9 Yes 1
CSF1-004 ENSP00000407317
ENST00000420111
P09603
Show all »
Show » Show » 256 29.2 Yes 1
CSF1-005 ENSP00000433837
ENST00000488198
E9PJA2
Show all »
Show » 285 31.2 No 0
CSF1-006 ENSP00000434527
ENST00000527192
E9PQ08
Show all »
Show » Show » 150 17.3 Yes 0
CSF1-007 ENSP00000431547
ENST00000525659
E9PKP4
Show all »
Show » 113 13.3 No 0
CSF1-008 ENSP00000349854
ENST00000357302
H7BY18
Show all »
Show » Show » 119 13.4 Yes 0
CSF1-201 ENSP00000342718
ENST00000344188
P09603
Show all »
Show » Show » 438 47.9 Yes 1