KCND2

GENE INFORMATION

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Gene name

KCND2 (HGNC Symbol)

Synonyms

KIAA1044, Kv4.2, RK5

Description

potassium voltage-gated channel, Shal-related subfamily, member 2 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q31.31

Chromosome location (bp)

119913722 - 120390385

Ensembl

ENSG00000184408 (version 73.37)

Entrez gene

3751

UniProt

Q9NZV8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NZV8

Antibodypedia

KCND2 antibodies
 

PROTEIN VIEW

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KCND2-001
 
KCND2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCND2-001 ENSP00000333496
ENST00000331113
Q9NZV8
Show all »
Show » Show » 630 70.5 Yes 6
KCND2-002 ENSP00000415463
ENST00000425288
177 19.5 No 0