KCNH7

GENERAL INFORMATION

? »

Gene name

KCNH7

Gene description

Potassium voltage-gated channel, subfamily H (eag-related), member 7

Protein class

Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

Membrane

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA018039
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast



PROTEIN EXPRESSION OVERVIEW

? »
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

? »

Gene name

KCNH7 (HGNC Symbol)

Synonyms

erg3, HERG3, Kv11.3

Description

Potassium voltage-gated channel, subfamily H (eag-related), member 7 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q24.2

Chromosome location (bp)

162371407 - 162838730

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184611 (version 78.38)

Entrez gene

90134

UniProt

Q9NS40 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NS40

Antibodypedia

KCNH7 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000328032
 
ENST00000332142
 
ENST00000618399
 
ENST00000621889
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNH7-001 ENSP00000331727
ENST00000332142
Q9NS40
Show all »
Show » Show » 1196 135 No 6
KCNH7-002 ENSP00000333781
ENST00000328032
Q9NS40
Show all »
Show » Show » 732 82.9 No 7
KCNH7-201 ENSP00000482818
ENST00000618399
Show » Show » 1096 123.7 No 6
KCNH7-202 ENSP00000483158
ENST00000621889
Show » Show » 630 71.3 No 7