UBE2G2

GENE INFORMATION

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Gene name

UBE2G2 (HGNC Symbol)

Synonyms

UBC7

Description

ubiquitin-conjugating enzyme E2G 2 (HGNC Symbol)

Entrez gene summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Chromosome

21 (Chromosome progress)

Cytoband

q22.3

Chromosome location (bp)

46188955 - 46221934

Ensembl

ENSG00000184787 (version 73.37)

Entrez gene

7327

UniProt

P60604 (UniProt - Evidence at protein level)

neXtProt

NX_P60604

Antibodypedia

UBE2G2 antibodies
 

PROTEIN VIEW

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UBE2G2-001
 
UBE2G2-005
 
UBE2G2-010
 
UBE2G2-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBE2G2-001 ENSP00000338348
ENST00000345496
P60604
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Show » Show » 165 18.6 No 0
UBE2G2-005 ENSP00000331384
ENST00000330942
P60604
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Show » Show » 137 15.6 No 0
UBE2G2-010 ENSP00000420671
ENST00000478200
F8WDB1
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Show » 99 11.1 No 0
UBE2G2-011 ENSP00000418423
ENST00000491513
F8WCB9
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48 5.3 No 0