HGS

GENE INFORMATION

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Gene name

HGS (HGNC Symbol)

Synonyms

Hrs, Vps27, ZFYVE8

Description

hepatocyte growth factor-regulated tyrosine kinase substrate (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]

Chromosome

17 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

79650356 - 79670168

Ensembl

ENSG00000185359 (version 73.37)

Entrez gene

9146

UniProt

O14964 (UniProt - Evidence at protein level)

neXtProt

NX_O14964

Antibodypedia

HGS antibodies
 

PROTEIN VIEW

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HGS-001
 
HGS-003
 
HGS-008
 
HGS-011
 
HGS-013
 
HGS-017
 
HGS-018
 
HGS-019
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HGS-001 ENSP00000331201
ENST00000329138
O14964
Show all »
Show » 777 86.2 No 0
HGS-003 ENSP00000459685
ENST00000571518
I3L2H4
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Show » 59 7 No 0
HGS-008 ENSP00000458987
ENST00000572392
I3L1P5
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Show » 263 30 No 0
HGS-011 ENSP00000458603
ENST00000577012
I3L165
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Show » 71 8.4 No 0
HGS-013 ENSP00000458775
ENST00000571237
I3L1E3
Show all »
Show » 292 32.4 No 0
HGS-017 ENSP00000460130
ENST00000575078
I3L326
Show all »
Show » 110 12 No 0
HGS-018 ENSP00000458789
ENST00000573320
63 6.8 No 0
HGS-019 ENSP00000460165
ENST00000570652
38 3.8 No 0