MAPK11

GENE INFORMATION

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Gene name

MAPK11 (HGNC Symbol)

Synonyms

p38-2, p38Beta, PRKM11, SAPK2

Description

mitogen-activated protein kinase 11 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [provided by RefSeq, Jul 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

50702142 - 50709196

Ensembl

ENSG00000185386 (version 73.37)

Entrez gene

5600

UniProt

Q15759 (UniProt - Evidence at protein level)

neXtProt

NX_Q15759

Antibodypedia

MAPK11 antibodies
 

PROTEIN VIEW

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MAPK11-001
 
MAPK11-002
 
MAPK11-003
 
MAPK11-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAPK11-001 ENSP00000333685
ENST00000330651
Q15759
Show all »
Show » Show » 364 41.4 No 0
MAPK11-002 ENSP00000409136
ENST00000417877
F8WDP4
Show all »
Show » 163 18.5 No 0
MAPK11-003 ENSP00000379113
ENST00000395764
Q15759
Show all »
Show » Show » 364 41.4 No 0
MAPK11-201 ENSP00000406921
ENST00000449719
B7Z630
Show all »
Show » 213 23.6 No 0