MRPL30

GENE INFORMATION

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Gene name

MRPL30 (HGNC Symbol)

Synonyms

MRP-L28, RPML28

Description

mitochondrial ribosomal protein L30 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene. [provided by RefSeq, Mar 2011]

Chromosome

2 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

99771461 - 99814089

Ensembl

ENSG00000185414 (version 73.37)

Entrez gene

51263

UniProt

Q8TCC3 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TCC3

Antibodypedia

MRPL30 antibodies
 

PROTEIN VIEW

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MRPL30-001
 
MRPL30-003
 
MRPL30-005
 
MRPL30-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL30-001 ENSP00000338057
ENST00000338148
Q8TCC3
Show all »
Show » Show » 161 18.5 No 0
MRPL30-003 ENSP00000386752
ENST00000409841
Q8TCC3
Show all »
Show » Show » 161 18.5 No 0
MRPL30-005 ENSP00000386970
ENST00000409145
B8ZZV5
Show all »
101 11.9 No 0
MRPL30-007 ENSP00000387111
ENST00000410042
Q8TCC3
Show all »
Show » Show » 131 15.2 No 0