TMEM179B

GENE INFORMATION

? »

Gene name

TMEM179B

Synonyms

Description

Transmembrane protein 179B (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

11

Cytoband

q12.3

Chromosome location (bp)

62554887 - 62557877

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185475 (version 75.37)

Entrez gene

102465448

UniProt

Q7Z7N9 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z7N9

Antibodypedia

TMEM179B antibodies
 

PROTEIN VIEW

? »
 
 
 
TMEM179B-001
 
TMEM179B-002
 
TMEM179B-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMEM179B-001 ENSP00000333697
ENST00000333449
Q7Z7N9
Show all »
Show » Show » 219 23.6 Yes 3
TMEM179B-002 ENSP00000433055
ENST00000533861
G3V185
Show all »
Show » 144 15.1 Yes 2
TMEM179B-004 ENSP00000436606
ENST00000526546
Show » 95 10.4 No 1