The Human Protein Atlas

GENE INFORMATION

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Gene name	PBX1
Synonyms
Description	pre-B-cell leukemia homeobox 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Chromosome	1 (Chromosome progress)
Cytoband	q23.3
Chromosome location (bp)	164524821 - 164868533
Ensembl	ENSG00000185630 (version 69.37)
Entrez gene	5087
UniProt	P40424
neXtProt	NX_P40424
Antibodypedia	PBX1 antibodies

PROTEIN VIEW

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PBX1-001		PBX1-002		PBX1-004		PBX1-007		PBX1-009		PBX1-012		PBX1-013		PBX1-015		PBX1-016		PBX1-017		PBX1-018		PBX1-019		PBX1-201		PBX1-202		PBX1-203

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
PBX1-001	ENSP00000405890 ENST00000420696	P40424 Show all » « Hide P40424 [Direct mapping] Pre-B-cell leukemia transcription factor 1 H0YLB0 [Target identity:75%; Query identity:100%] Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_a B1AN71 [Target identity:39%; Query identity:100%] Pre-B-cell leukemia homeobox 1 B1ANF4 [Target identity:39%; Query identity:100%] Pre-B-cell leukemia homeobox 1 F8WA05 [Target identity:39%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YKH1 [Target identity:36%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLT4 [Target identity:32%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:30%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:22%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 Q68DD6 [Target identity:22%; Query identity:100%] Putative uncharacterized protein DKFZp686B09108	Show » « Hide Transcription factors Mutated genes in cancer Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-dependent] GO:0006355 [regulation of transcription, DNA-dependent] GO:0006694 [steroid biosynthetic process] GO:0007548 [sex differentiation] GO:0008134 [transcription factor binding] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030154 [cell differentiation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0042127 [regulation of cell proliferation] GO:0043433 [negative regulation of sequence-specific DNA binding transcription factor activity] GO:0043565 [sequence-specific DNA binding] GO:0045665 [negative regulation of neuron differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048568 [embryonic organ development] GO:0048706 [embryonic skeletal system development]	430	46.6	No	0
PBX1-002	ENSP00000356872 ENST00000367897	P40424 Show all » « Hide P40424 [Direct mapping] Pre-B-cell leukemia transcription factor 1 Q53YC7 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia homeobox 1; Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_c B1AN71 [Target identity:48%; Query identity:100%] Pre-B-cell leukemia homeobox 1 B1ANF4 [Target identity:48%; Query identity:100%] Pre-B-cell leukemia homeobox 1 F8WA05 [Target identity:48%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YKH1 [Target identity:45%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLT4 [Target identity:40%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:37%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:27%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-dependent] GO:0006355 [regulation of transcription, DNA-dependent] GO:0006694 [steroid biosynthetic process] GO:0007548 [sex differentiation] GO:0008134 [transcription factor binding] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030154 [cell differentiation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043433 [negative regulation of sequence-specific DNA binding transcription factor activity] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	347	38.4	No	0
PBX1-004	ENSP00000452891 ENST00000468104	H0YLB0 Show all » « Hide H0YLB0 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_a H0YLT4 [Target identity:42%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:39%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 Q68DD6 [Target identity:30%; Query identity:100%] Putative uncharacterized protein DKFZp686B09108 H0YLM3 [Target identity:29%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	325	35.2	No	0
PBX1-007	ENSP00000341455 ENST00000340699	B1AN71 Show all » « Hide B1AN71 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia homeobox 1 B1ANF4 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia homeobox 1 F8WA05 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	170	18.2	No	0
PBX1-009	ENSP00000453163 ENST00000482110	H0YLD4 Show all » « Hide H0YLD4 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:75%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	129	14.3	No	0
PBX1-012	ENSP00000453188 ENST00000559240	H0YLF5 Show all » « Hide H0YLF5 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 B1AN71 [Target identity:50%; Query identity:100%] Pre-B-cell leukemia homeobox 1 B1ANF4 [Target identity:50%; Query identity:100%] Pre-B-cell leukemia homeobox 1 F8WA05 [Target identity:50%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YKH1 [Target identity:46%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLT4 [Target identity:41%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:38%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:28%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	339	37	No	0
PBX1-013	ENSP00000452804 ENST00000559578	H0YKH1 Show all » « Hide H0YKH1 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:61%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	159	17.6	No	0
PBX1-015	ENSP00000453130 ENST00000560469	H0YLB0 Show all » « Hide H0YLB0 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_a H0YLT4 [Target identity:42%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:39%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 Q68DD6 [Target identity:30%; Query identity:100%] Putative uncharacterized protein DKFZp686B09108 H0YLM3 [Target identity:29%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	325	35.2	No	0
PBX1-016	ENSP00000452869 ENST00000496120	H0YKN0 Show all » « Hide H0YKN0 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLB0 [Target identity:87%; Query identity:100%] Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_a H0YLT4 [Target identity:37%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:34%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:26%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 Q68DD6 [Target identity:26%; Query identity:100%] Putative uncharacterized protein DKFZp686B09108	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	370	40	Yes	0
PBX1-017	ENSP00000452727 ENST00000560641	H0YLB0 Show all » « Hide H0YLB0 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_a H0YLT4 [Target identity:42%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:39%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 Q68DD6 [Target identity:30%; Query identity:100%] Putative uncharacterized protein DKFZp686B09108 H0YLM3 [Target identity:29%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	325	35.2	No	0
PBX1-018	ENSP00000453262 ENST00000559560	H0YLM3 Show all » « Hide H0YLM3 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	97	10.5	No	0
PBX1-019	ENSP00000453331 ENST00000558837	H0YLT4 Show all » « Hide H0YLT4 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:92%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:69%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	139	15.6	No	0
PBX1-201	ENSP00000384856 ENST00000401534	P40424 Show all » « Hide P40424 [Direct mapping] Pre-B-cell leukemia transcription factor 1 Q53YC7 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia homeobox 1; Pre-B-cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1, isoform CRA_c B1AN71 [Target identity:48%; Query identity:100%] Pre-B-cell leukemia homeobox 1 B1ANF4 [Target identity:48%; Query identity:100%] Pre-B-cell leukemia homeobox 1 F8WA05 [Target identity:48%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YKH1 [Target identity:45%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLT4 [Target identity:40%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:37%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:27%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-dependent] GO:0006355 [regulation of transcription, DNA-dependent] GO:0006694 [steroid biosynthetic process] GO:0007548 [sex differentiation] GO:0008134 [transcription factor binding] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030154 [cell differentiation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043433 [negative regulation of sequence-specific DNA binding transcription factor activity] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	347	38.4	No	0
PBX1-202	ENSP00000439943 ENST00000540236	F5H4U9 Show all » « Hide F5H4U9 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 B1AN71 [Target identity:40%; Query identity:100%] Pre-B-cell leukemia homeobox 1 B1ANF4 [Target identity:40%; Query identity:100%] Pre-B-cell leukemia homeobox 1 F8WA05 [Target identity:40%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YKH1 [Target identity:37%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLT4 [Target identity:33%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:30%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:23%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	420	46.3	No	0
PBX1-203	ENSP00000440869 ENST00000540246	B7Z774 Show all » « Hide B7Z774 [Target identity:100%; Query identity:100%] Pre-B-cell leukemia transcription factor 1; cDNA FLJ52874, highly similar to Pre-B-cell leukemia transcription factor 1 H0YLT4 [Target identity:46%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLD4 [Target identity:42%; Query identity:100%] Pre-B-cell leukemia transcription factor 1 H0YLM3 [Target identity:32%; Query identity:100%] Pre-B-cell leukemia transcription factor 1	Show » « Hide Transcription factors Mutated genes in cancer Potentially secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0001655 [urogenital system development] GO:0001658 [branching involved in ureteric bud morphogenesis] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0008284 [positive regulation of cell proliferation] GO:0009887 [organ morphogenesis] GO:0009952 [anterior/posterior pattern specification] GO:0009954 [proximal/distal pattern formation] GO:0030278 [regulation of ossification] GO:0030325 [adrenal gland development] GO:0030326 [embryonic limb morphogenesis] GO:0035162 [embryonic hemopoiesis] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] GO:0048536 [spleen development] GO:0048538 [thymus development] GO:0048706 [embryonic skeletal system development]	301	33	No	0

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.