KCNIP4

GENE INFORMATION

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Gene name

KCNIP4 (HGNC Symbol)

Synonyms

CALP, KCHIP4, MGC44947

Description

Kv channel interacting protein 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p15.2

Chromosome location (bp)

20730239 - 21950422

Ensembl

ENSG00000185774 (version 73.37)

Entrez gene

80333

UniProt

Q6PIL6 (UniProt - Evidence at protein level)

neXtProt

NX_Q6PIL6

Antibodypedia

KCNIP4 antibodies
 

PROTEIN VIEW

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KCNIP4-001
 
KCNIP4-002
 
KCNIP4-003
 
KCNIP4-004
 
KCNIP4-006
 
KCNIP4-009
 
KCNIP4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNIP4-001 ENSP00000371583
ENST00000382148
Q6PIL6
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Show » Show » 225 26.3 No 0
KCNIP4-002 ENSP00000371585
ENST00000382150
Q6PIL6
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Show » Show » 229 26.5 No 1
KCNIP4-003 ENSP00000399080
ENST00000447367
Q6PIL6
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Show » Show » 216 25 No 0
KCNIP4-004 ENSP00000371587
ENST00000382152
Q6PIL6
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Show » Show » 250 28.7 No 0
KCNIP4-006 ENSP00000445321
ENST00000515786
F5H395
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34 3.7 No 0
KCNIP4-009 ENSP00000423257
ENST00000509207
Q6PIL6
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Show » Show » 188 21.9 No 0
KCNIP4-201 ENSP00000351892
ENST00000359001
Q6PIL6
Show all »
Show » Show » 188 21.9 No 0