GRK1

GENE INFORMATION

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Gene name

GRK1 (HGNC Symbol)

Synonyms

GPRK1, RHOK, RK

Description

G protein-coupled receptor kinase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]

Chromosome

13 (Chromosome progress)

Cytoband

q34

Chromosome location (bp)

114321470 - 114440708

Ensembl

ENSG00000185974 (version 73.37)

Entrez gene

6011

UniProt

Q15835 (UniProt - Evidence at protein level)

neXtProt

NX_Q15835

Antibodypedia

GRK1 antibodies
 

PROTEIN VIEW

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GRK1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRK1-001 ENSP00000334876
ENST00000335678
Q15835
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