CYP4F2

GENE INFORMATION

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Gene name

CYP4F2

Synonyms

Description

cytochrome P450, family 4, subfamily F, polypeptide 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.12

Chromosome location (bp)

15988834 - 16008930

Ensembl

ENSG00000186115 (version 73.37)

Entrez gene

8529

UniProt

P78329 (UniProt - Evidence at protein level)

neXtProt

NX_P78329

Antibodypedia

CYP4F2 antibodies
 

PROTEIN VIEW

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CYP4F2-001
 
CYP4F2-003
 
CYP4F2-004
 
CYP4F2-005
 
CYP4F2-007
 
CYP4F2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP4F2-001 ENSP00000221700
ENST00000221700
P78329
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Show » Show » 520 59.9 Yes 0
CYP4F2-003 ENSP00000464999
ENST00000592328
K7EJ29
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Show » Show » 520 59.9 Yes 0
CYP4F2-004 ENSP00000467443
ENST00000587671
K7EPM0
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60 6.1 No 0
CYP4F2-005 ENSP00000465514
ENST00000586927
K7EK90
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Show » Show » 154 17.6 No 1
CYP4F2-007 ENSP00000467846
ENST00000589654
Show » 74 8.9 No 0
CYP4F2-201 ENSP00000011989
ENST00000011989
B4DV75
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Show » 190 21.7 No 0