FFAR4

GENERAL INFORMATION

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Gene name

FFAR4

Gene description

Free fatty acid receptor 4

Protein class

G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (adipose tissue, colon, lung, rectum)
GTEx:Tissue enhanced (colon)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in a selected group of tissues, most abundant in rectum. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA042563
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (adipose tissue, colon, lung, rectum)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (colon)

Organ

Expression



GENE INFORMATION

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Gene name

FFAR4 (HGNC Symbol)

Synonyms

GPR120, GPR129, O3FAR1, PGR4

Description

Free fatty acid receptor 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Chromosome

10

Cytoband

q23.33

Chromosome location (bp)

93566665 - 93604480

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186188 (version 78.38)

Entrez gene

338557

UniProt

Q5NUL3 (UniProt - Evidence at protein level)

neXtProt

NX_Q5NUL3

Antibodypedia

FFAR4 antibodies


PROTEIN BROWSER

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ENST00000371481
 
ENST00000371483
 
ENST00000604414
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FFAR4-001 ENSP00000360536
ENST00000371481
Q5NUL3
Show all »
Show » Show » 361 40.5 No 7
FFAR4-002 ENSP00000360538
ENST00000371483
Q5NUL3
Show all »
Show » Show » 377 42.2 No 7
FFAR4-003 ENSP00000474477
ENST00000604414
S4R3L2
Show all »
Show » Show » 236 25.8 No 5