BTLA

GENE INFORMATION

? »

Gene name

BTLA (HGNC Symbol)

Synonyms

BTLA1, CD272

Description

B and T lymphocyte associated (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]

Chromosome

3 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

112182815 - 112218408

Ensembl

ENSG00000186265 (version 73.37)

Entrez gene

151888

UniProt

Q7Z6A9 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z6A9

Antibodypedia

BTLA antibodies
 

PROTEIN VIEW

? »
 
 
 
BTLA-001
 
BTLA-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BTLA-001 ENSP00000333919
ENST00000334529
Q7Z6A9
Show all »
Show » Show » 289 32.8 No 1
BTLA-002 ENSP00000373178
ENST00000383680
Q7Z6A9
Show all »
Show » Show » 241 27.3 No 0