DEFB106A

GENERAL INFORMATION

? »

Gene name

DEFB106A

Gene description

Defensin, beta 106A

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Not detected
GTEx:Not detected

Protein evidence

Evidence at protein level

Protein localization

Extracellular deposits and cytoplasmic expression in epididymis.

ANTIBODY RELIABILITY

? »

Data reliability
description

Caution, targets protein from more than one gene. Secreted protein, tissue location of RNA and protein might differ and correlation is complex. External characterization data supports antibody staining but no internal RNA data available for correlation.

Data reliability

Uncertain based on 1 antibody.
HPA045592
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Epididymis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Not detected

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

? »

Gene name

DEFB106A (HGNC Symbol)

Synonyms

DEFB-6, DEFB106

Description

Defensin, beta 106A (HGNC Symbol)

Entrez gene summary

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

7825172 - 7829053

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186579 (version 78.38)

Entrez gene

245909

UniProt

Q8N104 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N104

Antibodypedia

DEFB106A antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000335186
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB106A-001 ENSP00000335307
ENST00000335186
Q8N104
Show all »
Show » Show » 65 7.4 Yes 0