FGF3

GENE INFORMATION

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Gene name

FGF3 (HGNC Symbol)

Synonyms

HBGF-3, INT2

Description

fibroblast growth factor 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

69624992 - 69633792

Ensembl

ENSG00000186895 (version 73.37)

Entrez gene

2248

UniProt

P11487 (UniProt - Evidence at protein level)

neXtProt

NX_P11487

Antibodypedia

FGF3 antibodies
 

PROTEIN VIEW

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FGF3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF3-001 ENSP00000334122
ENST00000334134
P11487
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