MRPS21

GENE INFORMATION

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Gene name

MRPS21

Synonyms

Description

mitochondrial ribosomal protein S21 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q21.2

Chromosome location (bp)

150266289 - 150281414

Ensembl

ENSG00000187145 (version 73.37)

Entrez gene

54460

UniProt

P82921 (UniProt - Evidence at protein level)

neXtProt

NX_P82921

Antibodypedia

MRPS21 antibodies
 

PROTEIN VIEW

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MRPS21-001
 
MRPS21-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS21-001 ENSP00000312395
ENST00000309092
P82921
Show all »
Show » Show » 87 10.7 No 0
MRPS21-002 ENSP00000358080
ENST00000369084
P82921
Show all »
Show » Show » 87 10.7 No 0