Fields »

SUBCELLULAR LOCATION

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Main location(s)

Nucleus but not nucleoli

Additional location(s)

Plasma membrane, Aggresome 

Staining summary

Mainly localized to the nucleus. Additionally localized to the plasma membrane and aggresomes.

Reliability (APE)

Medium

Antibodies in assay

HPA020406, HPA020413
 

Antibody HPA020406

 

Antibody HPA020413

 

         Cell line A-431

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Location(s)

Nucleus but not nucleoli Nucleus but not nucleoli 

Staining characteristics

  

Staining intensity

Strong Moderate 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Nucleus but not nucleoli, Aggresome Nucleus but not nucleoli, Plasma membrane 

Staining characteristics

Speckle Speckle 

Staining intensity

Strong Moderate 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

  Nucleus but not nucleoli, Plasma membrane 

Staining characteristics

   

Staining intensity

  Weak 

Validation

  
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

   

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & aggresome.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & plasma membrane.
 

Summary

Staining of nucleus in A-431. Staining of nucleus and aggresome in U-2 OS.   Staining of nucleus in all three cell lines with additional staining of plasma membrane in U-251 MG and U-2 OS.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cell overview
Nucleus but not nucleoli
Plasma membrane