SIRT7

GENE INFORMATION

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Gene name

SIRT7

Synonyms

Description

Sirtuin 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

79869815 - 79879199

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187531 (version 75.37)

Entrez gene

51547

UniProt

Q9NRC8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRC8

Antibodypedia

SIRT7 antibodies
 

PROTEIN VIEW

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SIRT7-001
 
SIRT7-008
 
SIRT7-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SIRT7-001 ENSP00000329466
ENST00000328666
Q9NRC8
Show all »
Show » Show » 400 44.9 No 0
SIRT7-008 ENSP00000461044
ENST00000572902
I3L480
Show all »
Show » Show » 150 17.1 No 0
SIRT7-013 ENSP00000459524
ENST00000575360
I3L2A4
Show all »
Show » Show » 116 13.3 No 0